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02011nam a22003015i 4500 |
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110504s2011 xxu| s |||| 0|eng d |
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|a 9781441984173
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| 024 |
7 |
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|a 10.1007/978-1-4419-8417-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Targeted Drug Strategies for Cancer and Inflammation /
|c edited by Ann L. Jackman, Christopher P. Leamon.
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| 250 |
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|a 1st ed. 2011.
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| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2011.
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| 300 |
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|a XI, 254 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Biological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1) -- Folate Receptors and Therapeutic Applications -- Hormonal Control of Folate Receptor Genes -- Folate Receptor Targeted Radionuclide Imaging Agents -- Folate receptor targeted thymidylate synthase inhibitors -- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry -- Folate-receptor targeted cancer chemotherapy -- Anti-FR antibody generation and engineering: development of new therapeutic tools -- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases -- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-.
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| 650 |
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|a Cancer research.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
1 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
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| 700 |
1 |
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|a Jackman, Ann L.
|e editor.
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| 700 |
1 |
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|a Leamon, Christopher P.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|