Targeted Drug Strategies for Cancer and Inflammation /
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2011.
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| Edición: | 1st ed. 2011. |
| Materias: |
Tabla de Contenidos:
- Biological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1)
- Folate Receptors and Therapeutic Applications
- Hormonal Control of Folate Receptor Genes
- Folate Receptor Targeted Radionuclide Imaging Agents
- Folate receptor targeted thymidylate synthase inhibitors
- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry
- Folate-receptor targeted cancer chemotherapy
- Anti-FR antibody generation and engineering: development of new therapeutic tools
- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases
- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-.