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02960nam a22003255i 4500 |
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000294586 |
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20201019111030.0 |
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cr nn 008mamaa |
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190131s2019 xxu| s |||| 0|eng d |
| 020 |
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|a 9781493990658
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| 024 |
7 |
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|a 10.1007/978-1-4939-9065-8
|2 doi
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| 040 |
|
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Viral Vectors for Gene Therapy :
|b Methods and Protocols /
|c edited by Fredric P. Manfredsson, Matthew J. Benskey.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XIV, 328 p. 46 illus., 33 illus. in color. :
|b online resource.
|
| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1937
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| 505 |
0 |
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|a Basic Concepts in Viral Vector-Mediated Gene Therapy -- Design and Assembly of CRISPR/Cas9 Lentiviral and rAAV Vectors for Targeted Genome Editing -- Design, Construction, and Application of Transcription Activation-Like Effectors -- Practical Considerations for the use of DREADD and Other Chemogenetic Receptors to Regulate Neuronal Activity in the Mammalian Brain -- AAV Production using Baculovirus Expression Vector System -- Multimodal Production of Adeno-Associated Virus -- Generation of High Titer Pseudotyped Lentiviral Particles -- A Scalable Lentiviral Vector Production and Purification Method using Mustang Q Chromatography and Tangential Flow Filtration -- Current Use of Adenovirus Vectors and their Purification Methods -- Construction of Oncolytic Herpes Simplex Virus with Therapeutic Genes of Interest -- Poxviruses as Gene Therapy Vectors: Generating Poxviral Vectors Expressing Therapeutic Transgenes -- AAV Mediated Gene Delivery to the Mouse Liver -- Surgical Methods for Inner Ear Gene Delivery in Neonatal Mouse -- Gene Transfer to Mouse Kidney In Vivo -- Co-Delivery of a Short-Hairpin RNA and a shRNA-Resistant Replacement Gene with Adeno-Associated Virus: An Allele-Independent Strategy for Autosomal Dominant Retinal Disorders -- Localized Intra-Arterial Gene Delivery using AAV -- Stable Genetic Modification of Mesenchymal Stromal Cells Using Lentiviral Vectors -- Systemic Delivery of Adeno-Associated Viral Vectors in Mice and Dogs -- Intrathecal Delivery of AAV Vectors in Cynomolgus Macaques for CNS Gene Therapy and Gene Expression Analysis in Microdissected Motor Neurons -- Detailed Method for Intrathecal Delivery of Gene Therapeutics by Direct Lumbar Puncture in Mice -- Cerebromedullary Cistern Injection of Viral Vectors in Non-Human Primates.
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| 650 |
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0 |
|a Gene therapy.
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| 650 |
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0 |
|a Virology.
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| 650 |
1 |
4 |
|a Gene Therapy.
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| 650 |
2 |
4 |
|a Virology.
|
| 700 |
1 |
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|a Manfredsson, Fredric P.
|e editor.
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| 700 |
1 |
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|a Benskey, Matthew J.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|