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131028s2014 xxu| s |||| 0|eng d |
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|a 9781627037037
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| 024 |
7 |
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|a 10.1007/978-1-62703-703-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a miRNA Maturation :
|b Methods and Protocols /
|c edited by Christoph Arenz.
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| 250 |
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|a 1st ed. 2014.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2014.
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| 300 |
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|a X, 192 p. 50 illus., 29 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1095
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| 505 |
0 |
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|a The Pathway of miRNA Maturation -- Micro RNA Maturation and Human Disease -- Approaches to the Modulation of miRNA Maturation -- Expression Profiling of Components of the miRNA Maturation Machinery -- Primary microRNA Processing Assay Reconstituted using Recombinant Drosha and DGCR8 -- In-vivo processing Assay Based on a Dual Luciferase Reporter System to Evaluate DROSHA Enzymatic Activity -- Assaying Dicer-mediated miRNA Maturation by Means of Fluorescent Substrates -- A Fluorescence Correlation Spectroscopy-based Enzyme Assay for Human Dicer -- Detection of Micro RNA Maturation Using Unmodified pre-miRNA and Branched Rolling Circle Amplification -- Identification of Inhibitors of microRNA Function from Small Molecule Screens -- Quantitative RT-PCR Specific for Precursor and Mature miRNAs -- Cellular MicroRNA Sensors Based on Luciferase Reporters -- Inhibition of miRNA maturation by Peptide Nucleic Acids -- Molecular Methods for Validation of the Biological Activity of Peptide Nucleic Acids Targeting MicroRNAs -- Lentiviral Overexpression of miRNAs.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
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0 |
|a Gene expression.
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| 650 |
1 |
4 |
|a Human Genetics.
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| 650 |
2 |
4 |
|a Gene Expression.
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| 700 |
1 |
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|a Arenz, Christoph.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|