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01828nam a22003135i 4500 |
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20210615080835.0 |
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cr nn 008mamaa |
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120829s2013 xxu| s |||| 0|eng d |
| 020 |
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|a 9781461436768
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| 024 |
7 |
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|a 10.1007/978-1-4614-3676-8
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a p53 in the Clinics /
|c edited by Pierre Hainaut, Magali Olivier, Klas G. Wiman.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a X, 358 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Foreword -- p53 activities and the hallmarks of cancer -- The inheritance of p53 -- p53: Guardian of the metabolome -- The p53 family and stem cell biology -- Mutant p53-driven tumorigenesis -- Humanized p53 mouse models -- p53 models for mammary carcinogenesis -- TP53 somatic mutations: Prognostic and predictive value in human cancers -- Assessing TP53 status in human tumors - lessons from breast cancer -- TP53 germline mutations: Genetics of Li-Fraumeni Syndrome -- TP53 gene therapy -- Upstream targets in the p53 pathway -- p53-reactivating molecules as research tools and anti-cancer drugs -- Restoring mutant p53 activity -- p53-immunotherapy of cancer -- Designing p53 trials: a surgical oncologist view -- p53 in the clinic: a pathologist view -- p53 in genetic counseling -- Index.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Pharmacology.
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| 650 |
1 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
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| 700 |
1 |
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|a Hainaut, Pierre.
|e editor.
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| 700 |
1 |
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|a Olivier, Magali.
|e editor.
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| 700 |
1 |
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|a Wiman, Klas G.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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