p53 in the Clinics /
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2013.
|
| Edición: | 1st ed. 2013. |
| Materias: |
Tabla de Contenidos:
- Foreword
- p53 activities and the hallmarks of cancer
- The inheritance of p53
- p53: Guardian of the metabolome
- The p53 family and stem cell biology
- Mutant p53-driven tumorigenesis
- Humanized p53 mouse models
- p53 models for mammary carcinogenesis
- TP53 somatic mutations: Prognostic and predictive value in human cancers
- Assessing TP53 status in human tumors - lessons from breast cancer
- TP53 germline mutations: Genetics of Li-Fraumeni Syndrome
- TP53 gene therapy
- Upstream targets in the p53 pathway
- p53-reactivating molecules as research tools and anti-cancer drugs
- Restoring mutant p53 activity
- p53-immunotherapy of cancer
- Designing p53 trials: a surgical oncologist view
- p53 in the clinic: a pathologist view
- p53 in genetic counseling
- Index.