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03194nam a22003255i 4500 |
| 001 |
978-0-387-36534-3 |
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20191026222603.0 |
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cr nn 008mamaa |
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100301s2007 xxu| s |||| 0|eng d |
| 020 |
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|a 9780387365343
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| 024 |
7 |
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|a 10.1007/978-0-387-36534-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Protein Misfolding, Aggregation and Conformational Diseases
|b Part B: Molecular Mechanisms of Conformational Diseases /
|c edited by Vladimir N. Uversky, Anthony Fink.
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| 250 |
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|a 1st ed. 2007.
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| 260 |
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|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 2007.
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| 300 |
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|a XXVI, 538 p. 112 illus., 14 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Protein Reviews ;
|v 6
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| 505 |
0 |
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|a Altered Protein Structure and Enhanced Aggregation/Deposition -- The Pathogenesis of Alzheimer’s Disease: General Overview -- Free Radicals, Metal Ions, and A? Aggregation and Neurotoxicity -- Progress in Understanding the Mechanisms of Neuronal Dysfunction and Degeneration in Parkinson’s Disease -- ?-Synuclein Aggregation and Parkinson’s Disease -- Cell Biology of ?-Synuclein: Implications in Parkinson’s Disease and Other Lewy Body Diseases -- Pathogenesis of Prion Diseases -- Mammalian Prion Protein -- The Yeast Prion Proteins Sup35p and Ure2p -- Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis -- Pancreatic Islet Amyloid and Diabetes -- ?2-Microglobulin and Dialysis-Related Amyloidosis -- Serum Amyloid A and AA Amyloidosis -- Point Mutations and Enhanced Protein Deposition -- Transthyretin and the Transthyretin Amyloidoses -- Human Lysozyme -- Serpins and the Diversity of Conformational Diseases -- Altered Protein Structure and Impaired Function -- Human Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis -- Understanding the Effects of Cancer-Associated Mutations in the Tumor Suppressor Protein p53: Structural Consequences of Mutations and Possible Ways of Rescuing Oncogenic Mutants -- Changes in Supramolecular Structure -- Protein Aggregation in Muscle Fibers and Respective Neuromuscular Disorders -- Muscular Dystrophies and Protein Mutations -- The Functional Consequences of Dystrophin Deficiency in Skeletal Muscles -- Eye Lens Proteins and Cataracts -- Altered Protein Structure and Changes in Cellular/Nuclear Function -- Glutamine/Asparagine-Rich Regions in Proteins and Polyglutamine Diseases -- Mechanistic Insights into the Polyglutamine Ataxias -- Molecular Pathogenesis of the Polyglutamine Disease: Spinal and Bulbar Muscular Atrophy -- Post-Translational Modification and Protein Conformational Diseases -- Protein Glycation and Cataract: A Conformational Disease -- Defective Glycosylation and Muscular Dystrophies.
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| 650 |
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0 |
|a Immunology.
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| 650 |
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0 |
|a Cell biology.
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| 650 |
1 |
4 |
|a Immunology.
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| 650 |
2 |
4 |
|a Cell Biology.
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| 700 |
1 |
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|a Uversky, Vladimir N.
|e editor.
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| 700 |
1 |
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|a Fink, Anthony.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-0-387-36534-3
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