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03078nam a22002895i 4500 |
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978-1-4939-3667-0 |
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20191027142421.0 |
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cr nn 008mamaa |
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160531s2016 xxu| s |||| 0|eng d |
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|a 9781493936670
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|a 10.1007/978-1-4939-3667-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Histone Deacetylases
|b Methods and Protocols /
|c edited by Sibaji Sarkar.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2016.
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| 300 |
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|a XII, 337 p. 52 illus., 31 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1436
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|a A Sensitive and Flexible Assay for Determining Histone Deacetylase 1 (HDAC1) Activity -- Detection of Sumo Modification of Endogenous Histone Deacetylase 2 (HDAC2) in Mammalian Cells -- Analysis of Epigenetic Regulation of Hypoxia-Induced Epithelial-Mesenchymal Transition in Cancer Cells by Quantitative Chromatin Immunoprecipitation of Histone Deacetylase 3 (HDAC3) -- Molecular and Functional Characterization of Histone Deacetylase 4 (HDAC4) -- Approaches for Studying the Subcellular Localization, Interactions, and Regulation of Histone Deacetylase 5 (HDAC5) -- Analysis of Expression and Functions of Histone Deacetylase 6 (HDAC 6) -- Analysis of Histone Deacetylase 7 (HDAC7) Alternative Splicing and Its Role in Embryonic Stem Cell Differentiation toward Smooth Muscle Lineage -- Large-Scale Overproduction and Purification of Recombinant Histone Deacetylase 8 (HDAC8) from the Human-Pathogenic Flatworm Schistosoma mansoni -- Visualization of Histone Deacetylase 9 (HDAC9) Spatiotemporal Subcellular Localization in Primary Neuron Cultures -- Expression and Function of Histone Deacetylase 10 (HDAC10) in B Cell Malignancies -- Functional Analysis of Histone Deacetylase 11 (HDAC11) -- Sirtuin1 (SIRT1) in the Acetylation of Downstream Target Proteins -- Protocols for Cloning, Expression, and Functional Analysis of Sirtuin2 (SIRT2) -- Cloning and Characterization of Sirtuin3 (SIRT3) -- Identification of Sirtuin4 (SIRT4) Protein Interactions: Uncovering Candidate Acyl-Modified Mitochondrial Substrates and Enzymatic Regulators -- Generation and Purification of Catalytically Active Recombinant Sirtuin5 (SIRT5) Protein -- Sirtuin6 (SIRT6) Activity Assays -- Molecular, Cellular, and Physiological Characterization of Sirtuin7 (SIRT7) -- HDAC Inhibitors -- Assessment of the Anti-Proliferative Activity of a BET Bromodomain Inhibitor as Single Agent and in Combination in Non-Hodgkin Lymphoma Cell Lines -- Screening the Impact of Sirtuin Inhibitors on Inflammatory and Innate Immune Responses of Macrophages and in a Mouse Model of Endotoxic Shock. .
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| 650 |
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|a Cell biology.
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| 650 |
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|a Cell Biology.
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| 700 |
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|a Sarkar, Sibaji.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-4939-3667-0
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