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02759nam a22003015i 4500 |
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978-1-59259-148-0 |
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20191027133318.0 |
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cr nn 008mamaa |
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100301s2001 xxu| s |||| 0|eng d |
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|a 9781592591480
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| 024 |
7 |
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|a 10.1385/1592591485
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Meningococcal Vaccines
|b Methods and Protocols /
|c edited by Andrew J. Pollard, Martin C.J. Maiden.
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| 250 |
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|a 1st ed. 2001.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2001.
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| 300 |
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|a XVII, 421 p. 20 illus.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Medicine,
|v 66
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| 505 |
0 |
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|a Meningococcal Vaccines and Vaccine Developments -- Immune Response and Host-Pathogen Interactions -- Purification of Capsular Polysaccharide -- Protein-Polysaccharide Conjugation -- N-Propionylation -- Outer Membrane Protein Purification -- Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease -- Methods for Manipulation of Transferrin-Binding Proteins -- Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins -- Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics -- Construction of porA Mutants -- Construction of LPS Mutants -- Recombinant Proteins in Vaccine Development -- Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries -- Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity -- Early Experiences with Nasal Vaccines against Meningococcal Disease -- Animal Models for Meningococcal Disease -- Determination of Antibody Responses to Meningococcal Antigens by ELISA -- Immunoblot Analysis of Sera from Patients and Vaccinees -- Serogroup B and C Serum Bactericidal Assays -- A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers -- Whole-Blood Model -- Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry -- T-Cell Responses Against Meningococcal Antigens -- CD4 T-Cell Epitope Mapping -- Epitope Mapping -- Meningococcal Vaccine Trials -- The Introduction of Group C Conjugate Meningococcal Vaccine into the UK.
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| 650 |
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|a Infectious diseases.
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| 650 |
1 |
4 |
|a Infectious Diseases.
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| 700 |
1 |
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|a Pollard, Andrew J.
|e editor.
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| 700 |
1 |
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|a Maiden, Martin C.J.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
0 |
|u https://doi.org/10.1385/1592591485
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