Meningococcal Vaccines Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Pollard, Andrew J. (Editor ), Maiden, Martin C.J. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2001.
Edición:1st ed. 2001.
Colección:Methods in Molecular Medicine, 66
Materias:
Acceso en línea:https://doi.org/10.1385/1592591485
Tabla de Contenidos:
  • Meningococcal Vaccines and Vaccine Developments
  • Immune Response and Host-Pathogen Interactions
  • Purification of Capsular Polysaccharide
  • Protein-Polysaccharide Conjugation
  • N-Propionylation
  • Outer Membrane Protein Purification
  • Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease
  • Methods for Manipulation of Transferrin-Binding Proteins
  • Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins
  • Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics
  • Construction of porA Mutants
  • Construction of LPS Mutants
  • Recombinant Proteins in Vaccine Development
  • Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries
  • Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity
  • Early Experiences with Nasal Vaccines against Meningococcal Disease
  • Animal Models for Meningococcal Disease
  • Determination of Antibody Responses to Meningococcal Antigens by ELISA
  • Immunoblot Analysis of Sera from Patients and Vaccinees
  • Serogroup B and C Serum Bactericidal Assays
  • A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers
  • Whole-Blood Model
  • Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry
  • T-Cell Responses Against Meningococcal Antigens
  • CD4 T-Cell Epitope Mapping
  • Epitope Mapping
  • Meningococcal Vaccine Trials
  • The Introduction of Group C Conjugate Meningococcal Vaccine into the UK.