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01882nam a22003015i 4500 |
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978-1-59259-340-8 |
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20191027032346.0 |
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cr nn 008mamaa |
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100301s2002 xxu| s |||| 0|eng d |
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|a 9781592593408
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024 |
7 |
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|a 10.1385/1592593402
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
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|a Transgenic Mouse Methods and Protocols
|c edited by Marten H. Hofker, Jan van Deursen.
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250 |
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|a 1st ed. 2002.
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260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2002.
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300 |
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|a 392 p. 80 illus., 4 illus. in color.
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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490 |
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|a Methods in Molecular Biology,
|v 209
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|a Introduction: The Use of Transgenic Mice in Biomedical Research -- Genetic Modification of the Mouse -- In Vitro Fertilization/Cryopreservation -- Transgene Design -- Generating Conditional Mouse Mutants via Tetracycline-Controlled Gene Expression -- Manipulating Large Insert Clones for Transgenesis -- Reporter Molecules in Genetically Engineered Mice -- Gene Targeting in Mouse Embryonic Stem Cells -- Conditional Knockout Mice -- Knockin Approaches -- Aggregation of Embryos and Embryonic Stem Cells -- Andenovirus-Mediated Gene Transfer -- Random ENU Mutagenesis -- Autopsy and Histologic Analysis of the Transgenic Mouse -- Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells -- Quantification of Atherosclerosis in Mice -- Genetically Modified Mice in Cancer Research -- Neuropathobiology in Transgenic Mice.
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650 |
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|a Cell biology.
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650 |
1 |
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|a Cell Biology.
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700 |
1 |
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|a Hofker, Marten H.
|e editor.
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700 |
1 |
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|a van Deursen, Jan.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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856 |
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|u https://doi.org/10.1385/1592593402
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