Transgenic Mouse Methods and Protocols

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hofker, Marten H. (Editor ), van Deursen, Jan. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2002.
Edición:1st ed. 2002.
Colección:Methods in Molecular Biology, 209
Materias:
Acceso en línea:https://doi.org/10.1385/1592593402
Tabla de Contenidos:
  • Introduction: The Use of Transgenic Mice in Biomedical Research
  • Genetic Modification of the Mouse
  • In Vitro Fertilization/Cryopreservation
  • Transgene Design
  • Generating Conditional Mouse Mutants via Tetracycline-Controlled Gene Expression
  • Manipulating Large Insert Clones for Transgenesis
  • Reporter Molecules in Genetically Engineered Mice
  • Gene Targeting in Mouse Embryonic Stem Cells
  • Conditional Knockout Mice
  • Knockin Approaches
  • Aggregation of Embryos and Embryonic Stem Cells
  • Andenovirus-Mediated Gene Transfer
  • Random ENU Mutagenesis
  • Autopsy and Histologic Analysis of the Transgenic Mouse
  • Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells
  • Quantification of Atherosclerosis in Mice
  • Genetically Modified Mice in Cancer Research
  • Neuropathobiology in Transgenic Mice.