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04300nam a22003255i 4500 |
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978-1-59259-840-3 |
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20191027052046.0 |
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cr nn 008mamaa |
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100301s2005 xxu| s |||| 0|eng d |
| 020 |
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|a 9781592598403
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| 024 |
7 |
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|a 10.1385/1592598404
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Molecular Toxicology Protocols
|c edited by Phouthone Keohavong, Stephen G. Grant.
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| 250 |
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|a 1st ed. 2005.
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| 260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2005.
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| 300 |
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|a XIV, 489 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 291
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| 505 |
0 |
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|a Analysis of DNA Adducts -- 32P-Postlabeling Analysis of DNA Adducts -- Modification of the 32P-Postlabeling Method to Detect a Single Adduct Species as a Single Spot -- DNA Isolation and Sample Preparation for Quantification of Adduct Levels by Accelerator Mass Spectrometry -- Fluoroimaging-Based Immunoassay of DNA Photoproducts in Ultraviolet-B-Irradiated Tadpoles -- Analysis of DNA Strand Cleavage at Abasic Sites -- Detection of Chromosomal and Genome-Wide Damage -- Premature Chromosome Condensation in Human Resting Peripheral Blood Lymphocytes for Chromosome Aberration Analysis Using Specific Whole-Chromosome DNA Hybridization Probes -- Mutagen-Induced Chromatid Breakage as a Marker of Cancer Risk -- Flow Cytometric Analysis of Micronuclei in Erythrocytes -- The Comet Assay -- Computerized Image Analysis Software for the Comet Assay -- The Comet-FISH Technique -- DNA Double-Strand Break Damage and Repair Assessed by Pulsed-Field Gel Electrophoresis -- Detection and Characterization of Surrogate Gene Mutation -- Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes -- Quantifying In Vivo Somatic Mutations Using Transgenic Mouse Model Systems -- Methods for Detecting Somatic Mutations In Vitro -- Molecular Analysis of Mutations in the Human HPRT Gene -- Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes -- The GPA In Vivo Somatic Mutation Assay -- Flow Cytometric Measurement of Mutant T Cells With Altered Expression of TCR -- Detection and Characterization of Cancer Gene Mutation -- Mutation Screening of the TP53 Gene by Temporal Temperature Gradient Gel Electrophoresis -- Analysis of K-RAS and P53 Mutations in Sputum Samples -- Allele-Specific Competitive Blocker-PCR Detection of Rare Base Substitution -- Gel-Based Nonradioactive Single-Strand Conformational Polymorphism and Mutation Detection -- Detection and Characterization of Oncogene Mutations in Preneoplastic and Early Neoplastic Lesions -- Detection of DNA Double-Strand Breaks and Chromosome Translocations Using Ligation-Mediated PCR and Inverse PCR -- Analysis of DNA Repair Mechanisms -- Microsatellite Instability -- Unscheduled DNA Synthesis -- Analysis of DNA Repair Using Transfection-Based Host Cell Reactivation -- An Immunoassay for Measuring Repair of Ultraviolet Photoproducts -- Analysis of DNA Double-Strand Break Repair by Nonhomologous End Joining in Cell-Free Extracts From Mammalian Cells -- Measuring Recombination Proficiency in Mouse Embryonic Stem Cells -- Array Technologies -- Strategies for Measurement of Biotransformation Enzyme Gene Expression -- Genotyping Technologies -- TaqMan® Fluorogenic Detection System to Analyze Gene Transcription in Autopsy Material -- Development of Quantitative Reverse Transcriptase PCR Assays for Measuring Gene Expression -- Apoptosis -- Quantification of Selective Phosphatidylserine Oxidation During Apoptosis -- Quantitative Method of Measuring Phosphatidylserine Externalization During Apoptosis Using Electron Paramagnetic Resonance Spectroscopy and Annexin-Conjugated Iron -- Detection of Programmed Cell Death in Cells Exposed to Genotoxic Agents Using a Caspase Activation Assay.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Biochemistry.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Keohavong, Phouthone.
|e editor.
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| 700 |
1 |
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|a Grant, Stephen G.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
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|u https://doi.org/10.1385/1592598404
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