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02546nam a22004095i 4500 |
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978-1-59745-234-2 |
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20191027002528.0 |
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cr nn 008mamaa |
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100301s2008 xxu| s |||| 0|eng d |
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|a 9781597452342
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7 |
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|a 10.1007/978-1-59745-234-2
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Prion Protein Protocols
|c edited by Andrew F. Hill.
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| 250 |
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|a 1st ed. 2008.
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| 260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2008.
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| 300 |
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|a XIV, 280 p. 43 illus., 5 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 459
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|a Cell Culture Models to Unravel Prion Protein Function and Aberrancies in Prion Diseases -- Investigation of PrPC Metabolism and Function in Live Cells -- Immunodetection of PrPSc Using Western and Slot Blotting Techniques -- Assaying Prions in Cell Culture -- Generation of Cell Lines Propagating Infectious Prions and the Isolation and Characterization of Cell-derived Exosomes -- Neurotoxicity of Prion Peptides on Cultured Cerebellar Neurons -- Understanding the Nature of Prion Diseases Using Cell-free Assays -- Methods for Conversion of Prion Protein into Amyloid Fibrils -- Amplification of Purified Prions In Vitro -- Expression and Purification of Full-Length Recombinant PrP of High Purity -- Analysis of PrP Conformation Using Circular Dichroism -- Effect of Copper on the De Novo Generation of Prion Protein Expressed in Pichia pastoris -- Biophysical Investigations of the Prion Protein Using Electron Paramagnetic Resonance -- Molecular Diagnosis of Human Prion Disease -- Analysis of Endogenous PrPC Processing in Neuronal and Non-neuronal Cell Lines -- Molecular Typing of PrPres in Human Sporadic CJD Brain Tissue -- Transgenic Mouse Models of Prion Diseases -- Quantitative Bioassay of Surface-bound Prion Infectivity.
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| 650 |
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|a Neurosciences.
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| 650 |
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|a Proteins .
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| 650 |
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|a Biochemistry.
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| 650 |
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|a Neurobiology.
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| 650 |
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|a Infectious diseases.
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| 650 |
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|a Cell biology.
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| 650 |
1 |
4 |
|a Neurosciences.
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| 650 |
2 |
4 |
|a Protein Science.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Neurobiology.
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| 650 |
2 |
4 |
|a Infectious Diseases.
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| 650 |
2 |
4 |
|a Cell Biology.
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| 700 |
1 |
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|a Hill, Andrew F.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-59745-234-2
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