Leukemia Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: So, Chi Wai Eric. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2009.
Edición:1st ed. 2009.
Colección:Methods in Molecular Biology, 538
Materias:
Acceso en línea:https://doi.org/10.1007/978-1-59745-418-6
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245 1 0 |a Leukemia  |b Methods and Protocols /  |c edited by Chi Wai Eric So. 
250 |a 1st ed. 2009. 
260 # # |a Totowa, NJ :  |b Humana Press :  |b Imprint: Humana,  |c 2009. 
300 |a XI, 428 p. 87 illus., 12 illus. in color.  |b online resource. 
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337 |a computer  |b c  |2 rdamedia 
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490 1 |a Methods in Molecular Biology,  |v 538 
505 0 |a An Overview: From Discovery of Candidate Mutations to Disease Modeling and Transformation Mechanisms of Acute Leukemia -- Backtracking of Leukemic Clones to Birth -- Fluorescence In Situ Hybridization (FISH) as a Tool for the Detection of Significant Chromosomal Abnormalities in Childhood Leukaemia -- Specialized Fluorescence In Situ Hybridization (FISH) Techniques for Leukaemia Research -- LDI-PCR: Identification of Known and Unknown Gene Fusions of the Human MLL Gene -- Panhandle PCR Approaches to Cloning MLL Genomic Breakpoint Junctions and Fusion Transcript Sequences -- MRD Detection in Acute Lymphoblastic Leukemia Patients Using Ig/TCR Gene Rearrangements as Targets for Real-Time Quantitative PCR -- Array-Based Comparative Genomic Hybridization as a Tool for Analyzing the Leukemia Genome -- Application of SNP Genotype Arrays to Determine Somatic Changes in Cancer -- Retroviral/Lentiviral Transduction and Transformation Assay -- Gene Expression Profiling of Leukemia Stem Cells -- Humanized Model to Study Leukemic Stem Cells -- Model Systems for Examining Effects of Leukemia Associated Oncogenes in Primary Human CD34+ Cells via Retroviral Transduction -- Ex Vivo Assays to Study Self-Renewal and Long-Term Expansion of Genetically Modified Primary Human Acute Myeloid Leukemia Stem Cells -- Identification and Characterization of Hematopoietic Stem and Progenitor Cell Populations in Mouse Bone Marrow by Flow Cytometry -- In Vitro Differentiation of Embryonic Stem Cells as a Model of Early Hematopoietic Development -- Analysis of the Mouse Placenta as a Hematopoietic Stem Cell Niche -- Identification of Protein Interaction Partners by the Yeast Two-Hybrid System -- Complete Array of HOX Gene Expression by RQ-PCR -- Genome-Wide Determination of DNA Methylation by Hpa II Tiny Fragment Enrichment by Ligation-Mediated PCR (HELP) for the Study of Acute Leukemias -- Chromatin Immunoprecipitation (ChIP) for Analysis of Histone Modifications and Chromatin-Associated Proteins. 
650 0 |a Cancer research. 
650 0 |a Oncology  . 
650 0 |a Laboratory medicine. 
650 1 4 |a Cancer Research. 
650 2 4 |a Oncology. 
650 2 4 |a Laboratory Medicine. 
700 1 |a So, Chi Wai Eric.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1007/978-1-59745-418-6