Telomeres and Telomerase in Aging, Disease, and Cancer Molecular Mechanisms of Adult Stem Cell Ageing /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Rudolph, K. Lenhard. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Materias:
Acceso en línea:https://doi.org/10.1007/978-3-540-73709-4
Tabla de Contenidos:
  • Telomere Shortening and Ageing
  • Cellular versus Organismal Aging
  • Telomere-Induced Senescence of Primary Cells
  • Telomeres, Senescence, Oxidative Stress, and Heterogeneity
  • Initiation of Genomic Instability, Cellular Senescence, and Organismal Aging by Dysfunctional Telomeres
  • Telomerase Mutations and Premature Ageing in Humans
  • Telomerase, Telomeres, and Stem Cell Aging
  • Mechanisms of Stem Cell Ageing
  • Senescence Signatures of Human Hematopoietic Stem Cells
  • Telomere Shortening Induces Cell Intrinsic Checkpoints and Environmental Alterations Limiting Adult Stem Cell Function
  • p16INK4a and Stem Cell Ageing: A Telomere-Independent Process?
  • Telomerase as a Potential Regulator of Tissue Progenitor Cells
  • Telomeres, DNA Damage and Cancer
  • Telomere Shortening and Telomerase Activation during Cancer Formation
  • Telomere Binding Proteins and Disease
  • Therapeutic Targets
  • Targeting Telomerase: Therapeutic Options for Cancer Treatment
  • Werner Syndrome, Telomeres, and Stress Signaling: Implications for Future Therapies?.