The Selection of Doses in Chronic Toxicity/Carcinogenicity Studies Age-Associated (Geriatric) Pathology: Its Impact on Long-Term Toxicity Studies /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Grice, H.C. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1984.
Edición:1st ed. 1984.
Colección:Current Issues in Toxicology,
Materias:
Acceso en línea:https://doi.org/10.1007/978-3-642-49293-8
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024 7 |a 10.1007/978-3-642-49293-8  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 4 |a The Selection of Doses in Chronic Toxicity/Carcinogenicity Studies  |b Age-Associated (Geriatric) Pathology: Its Impact on Long-Term Toxicity Studies /  |c edited by H.C. Grice. 
250 |a 1st ed. 1984. 
260 # # |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 1984. 
300 |a VII, 114 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Current Issues in Toxicology, 
505 0 |a The Selection of Doses in Chronic Toxicity/Carcinogenicity Studies -- I. Introduction -- II. Factors Relating to the Dose Selection -- III. Principles for Dose Selection -- IV. Evaluation and Interpretation of Experimental Findings -- V. Recommendations for Future Research on Dose Selection -- VI. Summary -- VII. Glossary of Terms — As They Pertain to Toxicology -- VIII. References -- Age-Associated (Geriatric) Pathology: Its Impact on Long-Term Toxicity Studies -- I. Introduction -- II. Types of Long-Term Tests -- III. Factors Related to the Aging Process that Influence the Design and Conduct of Long-Term Rodent Studies -- IV. Age-Associated Diseases: How They Complicate Long-Term Toxicity Studies -- V. Effect of Aging on Drug Metabolism -- VI. Duration of Long-Term Studies -- VII. Cost of Conducting Toxicity Studies with Durations of 18, 24, or 30 Months -- VIII. Conclusions -- IX. Areas in Need of Future Research -- X. Summary -- XI. References. 
650 0 |a Pharmacology. 
650 0 |a Oncology  . 
650 0 |a Pharmacy. 
650 1 4 |a Pharmacology/Toxicology. 
650 2 4 |a Oncology. 
650 2 4 |a Pharmacy. 
700 1 |a Grice, H.C.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1007/978-3-642-49293-8