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02741nam a22003375i 4500 |
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978-3-642-78056-1 |
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20191023182718.0 |
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cr nn 008mamaa |
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121227s1993 gw | s |||| 0|eng d |
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|a 9783642780561
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|a 10.1007/978-3-642-78056-1
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 100 |
1 |
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|a Bodanszky, Miklos.
|e author.
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| 245 |
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|a Principles of Peptide Synthesis
|c by Miklos Bodanszky.
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| 250 |
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|a 2nd ed. 1993.
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| 260 |
# |
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|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 1993.
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| 300 |
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|a XII, 329 p. 26 illus.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Springer Lab Manuals
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|a I. Introduction -- References -- II. Activation and Coupling -- 1 Activation -- 2 Coupling -- 3 Coupling Methods -- References -- III. Reversible Blocking of Amino and Carboxyl Groups -- 1 General Aspects -- 2 Protection of the Carboxyl Group -- 3 Protection of the Amino Group -- References -- IV. Semipermanent Protection of Side Chain Functions -- 1 Carboxyl Groups of Aspartyl and Glutamyl Residues -- 2 Side Chain Amino Groups of Lysine and Ornithine -- 3 Hydroxyl Groups in Serine, Threonine and Tyrosine -- 4 The Sulfhydryl Group in Cysteine -- 5 The Guanidino Group of Arginine -- 6 Imidazole in Histidine -- 7 The Thioether in Methionine -- 8 The Indole Nitrogen in Tryptophan -- 9 The Carboxamide Groups in Asparagine and Glutamine -- References -- V. Side Reactions in Peptide Synthesis -- 1 Side Reactions Initiated by Proton Abstraction -- 2 Side Reactions Initiated by Protonation -- 3 Side Reactions Due to Overactivation -- 4 Side Reactions Related to Individual Amino Acid Residues -- References -- VI. Tactics and Strategy in Peptide Synthesis -- 1 Tactics -- 2 Strategies -- 3 Disulfide Bridges -- 4 Synthesis of Cyclic Peptides -- 5 Sequential Polypeptides -- 6 Partial Synthesis (Semisynthesis) -- References -- VII. Techniques for the Facilitation of Peptide Synthesis -- 1 Solid Phase Peptide Synthesis (SPPS) -- 2 Synthesis in Solution -- References -- VIII Recent Developments, New Trends -- 1 Formation of the Peptide Bond -- 2 Protecting Groups -- 3 Solid Phase Peptide Synthesis -- 4 Undesired Reactions in Peptide Synthesis -- 5 New Trends and Perspectives -- References.
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| 650 |
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|a Biochemistry.
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| 650 |
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|a Artificial intelligence.
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| 650 |
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|a Organic chemistry.
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| 650 |
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4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Artificial Intelligence.
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| 650 |
2 |
4 |
|a Organic Chemistry.
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| 710 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-3-642-78056-1
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